Implementing Six Sigma in Filling Process of InjectionMedicine:A Case Studies in Healthcare Industry

The research focuses on a pharmaceutical company operating in the and health-related products industry. filling process for injection medicines has experienced higher average rate of rejects, reaching 3.2% between September 2022 February 2023, which exceeds company's set limit 2.0%. This study aims to identify factors contributing problem provide recommendations reducing rejects using DMAIC method. During Define stage, SIPOC diagrams CTQ identification are utilized. Three categories identified: volume defects, imperfect sealing empty defects. Measure phase, employing Pareto diagram, highlights defects as most prevalent. DPMO calculation rejected medicinepreparation data results value 10630, with sigma level 3.80. Analyze stage involves identifying causing through use Fishbone Diagram. Furthermore, highest RPN 112, indicating potential failure, is determined be due insufficient supervision during production according FMEA. In Improve 5W+1H tools employed generate appropriate improvement proposals. These proposals documented, disseminated, adopted standard work guidelines.